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Research Highlights

Hundreds of scientists working at Cold Spring Harbor Laboratory contribute research published in major research journals, in the fields of Cancer, Neuroscience, Plant Biology, Quantitative Biology, and Genomics.

photo of Swentowsky, Lee, Lindsay, Kitagawa, Tran, and David Jackson

Corn 2.0

11/29/2021

Climate change and population growth are threatening our crops. CSHL Professor David Jackson is helping corn keep up with the demand. Read the story »

illustration of a single strand ribonucleic acid

The rise of RNA therapeutics

10/14/2021

RNA has been making waves as a new approach to prevent or treat diseases, including COVID-19 and spinal muscular atrophy. Read the story »

Think a census of humans is hard? Try counting their brain cells!

10/6/2021

CSHL researchers and other collaborators reached a milestone in a years-long effort to catalog the cells of the human, mouse, and monkey brains. Read the story »

illustration of DNA sequence with colored letters on black background containing mutation

Calculating the path of cancer

10/4/2021

A new mathematical approach is helping cancer researchers at CSHL determine how mutations lead to different behaviors in cancerous cells. Read the story »

photo of Barbara McClintocks transposon corn

The secret history of corn is revealed in its genome

8/5/2021

For the first time, scientists have assembled in-depth maps of dozens of corn genomes, filling in gaps related to key agricultural traits. Read the story »

Cataloging breast cells to find cancer origins

5/14/2021

CSHL scientists created a profile of normal breast tissue to pinpoint which cells might start down the path to cancer. Read the story »

photo of four ears of corn with different amounts of kernels

Tweaking corn kernels with CRISPR

2/22/2021

CRISPR genome editing can fast-forward the process of plant evolution. Researchers at CSHL are using the technique to increase kernel yield. Read the story »

AI researchers ask: What’s going on inside the black box?

2/8/2021

Although researchers have figured out how to train computers to recognize things, they have yet to understand how machines make those predictions. Read the story »

Building a corn cob—cell by cell, gene by gene

1/26/2021

CSHL scientists are piecing together the genes that control how corn develops. Read the story »

illustration of the human thymus gland in a body

How does anyone stay healthy in a world full of germs?

1/15/2021

Computational biology is uncovering the immune system’s tricks for identifying foreign invaders. Read the story »

image of cancer cell movement and metastases

Regulatory RNAs promote breast cancer metastasis

12/22/2020

A gene-regulating bit of RNA promotes breast cancer metastasis. Agents that destroy that RNA provide hope for a new drug. Read the story »

illustration of a South American capuchino seedeater

Birds of a feather do flock together

11/17/2020

Researchers found a genetic mechanism for how brand new species acquire distinct traits. Read the story »

Giving the immune system a double boost against cancer

10/30/2020

Immunotherapy enhances the body’s own defenses to kill cancer. A new regimen may increase the utility of these types of drugs. Read the story »

How to figure out what you don’t know

10/26/2020

Sometimes, what seems like a good way to understand the world turns out to be wrong. A new machine learning tool lets scientists find better answers. Read the story »

image of mouse brain motivational center

Reward and punishment take similar paths in the mouse brain

9/15/2020

One brain structure is involved with both positive and negative reinforcement types of learning. Read the story »

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